The Crosshair has an additional PCI-e x16 slot is the main difference. If you are doing a new build though, you'd probably be quite happy with a 890GX board instead.
http://www.newegg.com/Product/Product.aspx?Item=N82E16813131631&nm_mc=AFC-C8Junction&cm_mmc=AFC-C8Junction-_-RSSDailyDeals-_-na-_-na&AID=10521304&PID=3463938&SID=
It also has USB 3.0 support.