If you want the RAM to run at 1600MHz, that involves overclocking the CPU to 160MHz BCLK. You will also need to set the memory multiplier to 10x, or it is also known as FSB : DRAM ratio, which should be set to 2:10. If you leave it at stock 2:8, you will need to overclock the CPU's BCLK to 200MHz. Make sure you have a decent aftermarket cooler if you intend to push it this far. However, there is very little difference between 1600MHz and 1066MHz in reality.