Welcome to the forums,
Probably can, as long as you don't have a ton of drives and high OC voltage. But is it a good idea? No. Not a fan of anyone that goes rating a PSU at 750w but only provides 48a available combined on the 12v rail is being a little deceptive.http://www.apevia.com/ProductsInfo.asp?KEY=ATX-WA750W
A pair of 260s burn up 22.5a:http://mark.zoomcities.com/images/gfx/GFXpowerchartby3d.png
A pair of opticals and HDDs eat up 6a and the CPU depends on what you have. Could be 8a-15a depending on if you OC. Probably won't bust past the 48a, but come close. Running full load will wear on a units life if its not well built. And I know its not well built because that little red voltage selection switch means corners were cut because its cheaper and as a result, the power it produces is generally not as stable as a unit that adjust to input voltage on its own. Europe has banned PSUs that have that manual switch because it eats up too much power from the wall to get the same amount to the parts. For the sake of not blowing up your $350 worth of GPUs, I'd get something reliable with top notch reviews. You can use the PSU link in my sig to see a list of reviews. Anything in the 55a+ should work for you.