It won't, as long as you keep an eye out for the PCI-e frequency. Make sure it's manually set to 100MHz because some auto overclocking settings will also raise this too.
thanks so much for your reply, I never would have known that changing the FSB multiplier to reach 3.2 GHz could affect PCIe frequency!!
I will ensure to check PCIe frequency inside BIOS to keep on 100 MHz.