I don´t know, but i think yes, my motherboard just supports 1333Mhz not o.c. and my Ram is 1600MHz but my motherboard supports 1600Mhz o.c., and the CPU can had a o.c. to 4GHz (yes is one of the best's CPU (SK 775) for O.C.), I just had it to 3.4GHz (but i don´t increse the voltage because i see it here (http://www.tomshardware.com/reviews/dual-quad,1720-12.html),