Sure it will do it
Go for it
If you haven't bought your GPU, i suggest you look at radeon 5770
For a little price difference you will get DirectX 11 and noticeable gain in performance
Personally i like NVIDIA
thanks for all your replys my case shouldnt really be an issue there is a good 2-3 inches gap from the motherboard to the edge of the case mainly i am just worried about things like heatsincs etc that stick out blocking it - thats my main worry
HD5750 and GTS250 are neck to neck performance wise, but if they are the same price you would get the DX11 support with the ATI card which of course is only useful if you are running Windows Vista or 7.
It will go into the PCI-E slot no problem. The question is, will it fit in your case . I recommend using some measuring tape to see how much length you have. If the slot runs parallel to the Hard Drive then you may want to move it out of the way to another bay.