If you want to use it as a boot drive, you will indeed need a different motherboard.
If you want to use it as a _data_ drive, you can. If there is any data on it that you need, back it up. Delete all partitions. Use the Disk Mangler to re-initialize the drive, and initialize it as GPT, not the default MBR. Unless you have a very old motherboard, you should be able to see and use the entire 3 GB of the drive for data.