Depends on what cpu you're using and socket type. Most likely need more information on what kind of pc you have. Then we'd be able to determine what mobo within the platform you're running would suit your needs...
thanks for your fast reply, i want to build new high end pc for one of my friends.
he might take the 6 core cpu Extreme I7
with crossfire ATI 5970
4GB X 6= 24 GB ram
so which is best mob can handle all of these? or if you have any suggestion please write