My PSU has a 2x4-pin connector ready for the CPU power.. The only problem is that the Full-size tower is too full-size for the cable its reach. In short: It can't get there.
The only way to get any cable to the 2x4-pin with this PSU is to use an adapter, which I did on 2xmolex -> 6-pin.
In my previous case I did use the 2x4-pin so it is an option, but it should work any way, right?