Yes it can, but a lower clocked X2 will bottleneck that GPU in many games. The bigger question is, can your PSU handel it? If it can then go for it, if you are unsure, then perhaps you should research your PSU before you plug a GTS250 in your system and kill the whole thing.
 

billy05

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Jan 27, 2010
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18,510

My screen is black when i turn on my computer, I can not get a video on the screen.
 
Did you remember to plug in the PCIe 6 pin power connectors to the GPU?
Try removing and reseating the GPU, then double check all data and power cables in your system.

Please post the rest of your system specs including the PSU brand, wattage and +12v amperage.