It will have no effect & won't damage your CPU or MOBO. You just set your DRAM Voltage to 1.65V in your BIOS than set any required frequency & timing changes need to match the RAM specifications.
Do you mean i should manually change the bios voltage to 1.65V or would it be fine left at 1.5V?
Im looking at the TW3X4G1600C9D modules. They are listed on the website as compatible with my mb.