Okay... let look at it another way.
Do you plan to ever run 3 GPU's and a PhysX's card? If no... get either the ASUS Sabertooth X58 or ASUS P6X58D-E. If you do... than the Classified 3 is the logical choice!
I completely forgot about that! xDD Well i do plan on going 3-way SLi. Not exactly 3-way + PhysX. If anything 2-way + Physx is hell of alot of power for my gaming: a GTX 460 + GTS 250 for PhysX has pretty much held up all my games on the Highest settings with 30FPS+ on most. It would hit about (avg.) 28FPS on Metro 2033 using D11 with everything set on highest.
All right so then i'll put the C3 on my "Future upgrade in case of boredom - list".
Now i just noticed something about the Sabertooth x58. It has 2 x PCIe 2.0 and 1 x PCIe 1.0? What's up with that? lol