What do you do if your usb ports arnt working

Sound like a driver problem. Try re-installing the drivers for your motherboard chipset. If that does not work your USB controller may have gone bad. In that case you either have to get a new motherboard or a USB expansion card.

Which operating system are using? Which USB does it happen for, front panel or the ones on the rear of the motherboard?

Sometimes it's as simple as turning off your computer and unplugging it from the outlet. Press the power button and wait another minute. Plug the computer back in and start it up. This seems to work quite a bit, though not for everyone.

Did you check out whether your usb ports are given any connection, if yes then you try it by restarting your system as it would sometimes don't work because of power fluctuations.

I have the same problem. Running Windows 7 Ultimate 64-bit. I can only use one USB port at a time (mouse), and it hangs up when I try to plug anything else in, and will not recognize any USB drives. I purchased a PCI USB card, but it is apparently not compatible with 64-bit.   Any suggestions on a *cheap* USB expansion card, preferably with at least 4 ports?