The plot thickens. I can't boot into safe mode. I press F8 repeatedly while booting and get a bios box asking me if I want to boot using my HDD or either of my two DVD burners. If I continue pressing F8 nothing happens. If I select the HDD and press enter the machine boots normally. I've never seen this combination of issues before.
I have same problem, P55A chipset, XFX 5770 XXX edition. had a 5750 to start with, removed it for a temp nvidia card then to the 5770 in a month after installing Windows, and sicne then the ATI software is useless as well after trying a million things...
I hear you. It's not like this is my first experience with ATI. I used some of their boards before they were bought by AMD and had many of the sort of problems that are nearly impossible to track down or eliminate. I hoped it was different now. I'll wait until Nvidias new release and buy what's right for me and sell my 5750 to someone with more faith in ATI than me.
This is an old thread, but it's one of the top search results for "ccc won't run" so I wanted to post another possible solution here. My solution was to clear out the Windows GAC (Global Assembly Cache). In Windows 7, you can browse directly to "C:\Windows\assembly". Sort by "Public Key Token", then delete everything with the Token "90ba9c70f846762e" (ATI's key). You'll obviously need Administrator privileges. No reboot needed either. Reinstalled CCC and it ran perfectly!
The GAC lets you share DLL's that are the same version number. If it's in the GAC, any installer will NOT install a new DLL - it'll use the one in the GAC. If the GAC DLL is corrupted, you're majorly SOL.
When I reinstalled the CCC, it took longer to install then it had before. Presumably, this was due to the installer copying all the correct DLL's to my hard drive. And no ATI DLL's have made it back into my GAC.
To give credit to the original poster, here's the page I found this fix on: