Intermittent Hard Drive 'Disappearance'

Hello all,

I've been having an intermittent issue with any secondary SATA drive I plug in with 2 different motherboards. Sometimes, I will be able to see and use my hard drive and sometimes I will not be able to. This issue ONLY happens with my secondary SATA hard drive. My Primary OS drive and my DVD-ROM drive both show up every time on boot.

So far, I have upgraded my power supply to a 1250W, which is definitely sufficient for my setup. I have tried 2 different drives on my initial P8P67 Deluxe board and gotten the same problem with any SATA port I plug it into. I tried a BIOS update and still got the same issue. I figured it was perhaps an issue with being run at 6Gbps, but 4 of my ports are 3Gbps and it still had the issue when plugged into those. I also updated the Intel Rapid Storage Technology driver with the same results. This led me to believe it has defective SATA ports.

I am currently using a P8H61-M LE/CSM with the same setup and getting the same problem I got with the other board. I haven't tried my other hard drive, but I'm confident I will see the same thing again.

I have not tried a clean install of Windows yet and have not been able to recreate this issue without my 300GB Velociraptor plugged in. At this point, I am wondering if anyone can give me any other suggestions before I go ahead and wipe my drive.

Here's my setup:

OCZ X-1250
ASUS P8P67 Deluxe (ASUS P8H61-M LE/CSM was also available for testing purposes)
Intel Core i5-2500K
Kingston HyperX DDR3-1600MHz
Western Digital Velociraptor WD3000GLFS
Seagate Barracuda 1TB (Also tested with Western Digital WD2500JS)
LG DVD Burner
Sapphire Radeon HD 4890