Thanks. I appreciate options. I'm looking for specific, not general advice. For instance, the OCZ fan blows up or down, depending on mount, right? The Antec PSU blows out the back, which is suggested strongly for the Skeleton. Also, the Skeleton only holds two HD internally without mounting one to four more on the sides externally. If I want a system drive, SSD or not, then I only have one remaining space. Hence the 2 TB drive. If it's downfall is running hot, then the Skeleton design is maybe the best use of a questionable drive at a good price.
The QVL doesn't really matter. That's just the list of the RAM they have extensively tested on the board, not a list of all compatible RAM. G.Skill is a major RAM manufacturer. If they made RAM that was incompatible with one of Asus's major boards, they wouldn't be making much money. I wouldn't worry about it not being on the QVL.
As for the 1600 mhz, I have no idea where you'ver heard that. The speed and the amount of RAM you can use have no connection. The only thing that may be a little strange about 1600 mhz RAM is that it might default to 1333 mhz in BIOS, so you might have to set the speeds and timings manually, which is very easy to do.
To be honest, this is the first time I've heard that. Doing some searching seems to be that the problem lies with the board's memory controller being stressed too much by the voltages. Some posts on a couple RAM manufacturer's suggest that as long as you're careful with the voltage settings, you should be able to fill all the slots. You may want to go over to Mushkin's and Asus's forums and get an answer for sure though.