No not really chipset wise. G33 was succeeded by G41. But the differences are close to none. Other than a better OC.
BUT the Gigabyte board uses DDR3 RAM, so you will need new RAM.
IF your system is only an old dual core as I suspect, I would advise you rather get a new board AND cpu than spend money on an old outdated build.
my cpu is core2duo E8400 3ghz,can u suggest me a mobo supporting ddr2 ram?