Id say Neither.
Getting the GD80 is just wasting money asa it only has enhaced OC features compared to cheaper mobos, and the Biostar just aint trustworthy enough.
But overall quality/value wise the first one is better.
Considering you need "moving lots of Data to and from external Drives", you might want a USB3 mobo + a 1055T combo.
Thanks for the Quick Reply Timop...
If you would not recommend either combo do you have one in mind that is better for the same cost?
The GD80 has USB 3.0 and can OC fairly well (faster clock = quicker matlab runs) while the Biostar 890's have some good reviews out there which state that they are stable at 4.0Ghz....which is why I am having a hard time choosing between them