Do you plan to overclock? Typically I will install the hardware with stock settings then install the OS and appropriate drivers. ...then overclock / stress test (note your max temps when stress testing). ...then try unlocking. It can really be done in a multitude of ways.
NOTE: When unlocking your AMD processor you will not be able to read your core temps. Take your max temps while stress testing and add 4C to get a good idea where you are at with four cores enables (if you are able to unlock with no issues).