I have P5E-WS mb an my one of my friend suggest me to buy ASUS P5k PRO mb if i get PRO mb is there any performance deference?
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The main difference between X38 and P35 is that X38 supports CF at dual x16 mode;whereas, P35 chipset(almost all of them) support CF at x16x4 speed.So if you need CF support,go with X38;otherwise,go with a P35 board.
The best overclocking and performing s775 motherboard is hands down the P45.
For single card setups, P35/P45 will give you exactly the same performance as an X38/X48 board.