Thank you for the answer! I'm sorry for the confusion of my last question. What I meant was Is there a difference if I purchase 4 separate 4g sticks of the same ram vs 2 packs of 2 4g sticks, vs 1 pack of 4 4g sticks. I believe the term is matched pair?
I was planning on getting 16g 4x4 of the 1600 Vengeance for a Asus Maximus 4.
I suggest buying the matched kits of either 8GB or 16GB. They have been tested and certified to run together. Also, just as a side note, current generation AMD and Intel based MOBOs are just fine with 4GB modules.