Hello... with my experience with all Windows versions... when you change the motherboard, you must re-install OS... and re-activated... all other parts can be changed... But that makes sence, when it comes to having the proper drivers needed for the motherboard... and not having drivers conflicting or causing problems.
This is assuming you are changing the motherboard to a newer/upgraded type.
You cannot Reactivate a OEM disk on a different motherboard. I am asking if the upgrade changes the OEM license to a full retail license so I can then change the motherboard.