The 750 is a true quad core, while the 650 is a dual core with hyper threading giving it 2 physical cores and 4 logical cores, in multithreaded tasks its addition clock speed will help close the performance gap so they will perform fairly similarly, but if you OC the 750 will do better in any tasks that need more than 2 cores. The 650 also comes with integrated graphics on the CPU, not great but better than the IGPs they had on their old chipsets, any discrete GPU will best it easily but it can be good for cheaper low budget machines that just need some graphics.