For all those who are interested. I found the reason why the Lachesis Mouse does not respond at cold start-up. Using the Windows 7 operating system 64 bit, I ran a program compatibilty on both the Lachesis Mouse and the Lycosa Keyboard. The program compatiblity software indicates that both the Lachesis Mouse and the Lycosa Keyboard are incompatible with the Windows 7 software. The program compatibility indicates the both the Lachesis Mouse and the Lycosa Keyboard are most compatible with Windows XP service pack 2. So if you perform a right mouse click on the Lachesis icon and click on the properties tab you are able to access the compatibility tab. Then set the compatibilty to Windows XP service pack 2. The cursor should activate consistently at each start-up.