A Runtime Error has occurred. Do you wish to Debug?

when i start my PC there is a msg display on screen A Runtime error has occured do you wish to debug? line: 108, error:permission denied
so plz wat i have to do now
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  1. What to do now is provide more information. Does this happen while Windows is starting up, or after you log in? If you clear the message is Windows usable or not?

    If Windows is usable, I would read the event log and look for a cause. It could be as simple as some program starting up and trying to read something that you moved. More information, please.
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