From what I have read and from personal experience it is a good idea to keep at least 10% of the SSD space free. I don't know the space requirements for Cinema 4d and the other design software you have in mind but I do know that I am pleased with the performance of the Adobe CS6 Production Suite I have installed on the SSD. Premiere, Encore, After Effects, etc. all load very quickly compared to when they were installed on an HDD. I use the HDD for storage of the data files I use with those programs and am pleased with speed with which those files load when I open a project.