question. why are you even trying to use a 3.5 floppy at all.?
and if you have an empty hdd bay, get another hdd..
total waste of time and space using a 3.5 floppy.
but to answer your question, if you have the proper connectors lined up,
anything is possible so yes technically you can.
I hope you know that the 3.5 floppy and the hdd have different connection interfaces.
yes i know the connectors are different, and i have a floppy drive so i thought i might aswell use it somewhere and i dont intend for having many more hdds