Sure, any AM3 motherboard with four (4) available DIMM slot can run 4 sticks of RAM. No CPU on the market today, AMD or Intel, actually runs quad channel.
I would point out: you will get Better OC'ing performance on your RAM if you only have 2 sticks. You'll get higher frequencies at lower voltages every time. SOOOOO, I would definitely go for 2 x 4Gb sticks over any 4 x 2Gb setup. This is true for any AMD CPU any Intel CPU........
Get this: (for best performance)http://www.newegg.com/Product/Product.aspx?Item=N82E16820231428
NOT this: http://www.newegg.com/Product/Product.aspx?Item=N82E16820231325
Two 2 sticks of any brand, any speed, and any timings will Always Easier to run faster than 4 stick of same brand, timings, and speed... (at lower voltages too...)