That depends on the model of motherboard. Is that processor a 754, 939 or am2? As far as I can remember socker 754 only has a DDR controller. 939 may have a ddr2, and for sure am2 does. So if the socket is 754, then no. If it is 939, it`s case by case but a maybe since i cannot recall what memory controller the 939 uses. If it is am2 then more than likely the board supports ddr2, you can usually find the information by looking up the motherboards specifications on the manufacturer`s website.