Not really. The Phenom X6 will yield a lower platform cost, while not performing much worse than the i5. The fact is anything business isn't going to require much processing power, but things stack up and in turn the AMD will see a slight edge.
For Data security, I would suggest a RAID 1+0, or a SSD plus RAID 1 solution.
But to keep things simple you can simply use a Samsung F3 drive, plenty fast.