You can always create a page file on a different drive.
Also, don't know if it's still a problem, but there are glitches in the game, epecially the last level. Even with a patched game, I'd fall through the deck of the ship in certain areas and be trapped inside. I'd have to restart from my last save point to in order to continue. I have a HD4850 vid card.
Try running in DX9 instead of DX10.
Found another thread concerning this... notice, randomizer states he had the same problem I did, falling through the deck of the ship.http://www.tomshardware.com/forum/102949-13-crysis-final-boss-crashing-solved