I wouldnt' raid anything with that missmash of drives. Use the samsung as OS, ocz to install games, and the other two for storage drives.
You could configure some of that so it isn't a hassle to work with 4 drives letters if that was concern.
Ok, with that in mind, how would I configure the OCZ to display games on my desktop while the Samsung is running the OS. OR like you said, configure it so there isn't 4 drive letters.