I'm starting a new build an have a 180 GB Intel 330 SSD for O/S and 2 TB Seagate for storage. I have an extra 64 GB OCZ Octane 3 SSD. Can I use this drive to increase performance or should i just stick with the Intel/seagate configuration
You may be able to do so actually. You'll want a z77 board so that you get trim while raid is enabled (as raid is needed for SRT).
I think you setup a raid 0 array of the HDD and 64GB ssd to enable caching, but I've never setup SRT before so I'm not sure; you'll want to make sure SRT won't cache data from your 180GB ssd, since it's wasteful to cache data that is already on an SSD.