No, your CPU is not going to create any problem for your GPU. No need to panic for that.
NVIDIA's GeForce GTX 460 768MB-GDDR5 graphics card empowers DirectX-11 video games to deliver unmatched geometric realism at the $200 price point. Based on the same Fermi architecture that powers their high-end GeForce GTX 480 model, the NVIDIA GeForce GTX 460 delivers mid-range performance for gamers on a budget.
Metro 2033 (1680x1050) - GTX 460 struggles to produce 25 FPS with DirectX-11 anti-aliasing turned two to its lowest setting.
But still it makes the game playable, but all the DX 9 & DX 10 games you can play with ease at your comfortable resolution of 1920x1080.
You are making a good choice under DX 11, so go for it.