No. It simply won't identify the cpu correctly during the post. Serious issues are bluescreens, which are usually a memory issue, or freeze ups and reboots. It won't hurt to change boards, but if you've never done it before, you'll need to do some reading. Download the motherboard manual before ordering any board and read sections of it. Some are well written, some not. For any oem system (dell, hp, etc), your windows installation may only work with the original board or possibly with a replacement dell, hp board.