I am currently using the 0501 Bios, i have downloaded the 0606 bios update from the Asus website but everytime i try to run the installer it it just tries to install/update intel smart response technology? I have updated that and i have attempted with it running and with it disabled but still cant install the new bios! Any one know whats going on? I would prefer to update my bios through my OS as i have had very little experience working with bios, i have recently completed my first build and i have updated all my drivers etc but this wont seem to work?
I also am having issues with installing the drivers for my iGPU to work... This isnt a problem as i am happy running completely from my GTX580 but i tried to install lucid virtu and it said i didnt have a compatible GPU (iGPU) so i downloaded the drivers for it and it says my hardware is not compatible? (I have an i7 2600K)
ISRT is used when you have a mechanical HDD and an SSD - the idea is that you can use SSD smart caching to speed up the performance of your mechanical HDD - if you are not using an SSD - you don't require ISRT - and in fact it is pointless. Unless something's changed that I don't know about.
Anyway, your concern now is the BIOS:
Uninstall IRST, hopefully that will leave a clear path and your BIOS won't complain.
EDIT : I would add that whilst a new BIOS feature may improve performance - you should check that it improves the performance of YOUR computer. The BIOS can be a tricky thing at the best of times (I can't access mine at the moment - currently in a thread somewhere below this one) and should only be updated/flashed if you have made a backup of the original.
When you update the BIOS I recommend : Going into the BIOS/UEFI and update it via EZ Flash. You can use a USB stick with the update on it but also have another stick to copy your current version - in case there is a failure.
After it's done, simply go back into the BIOS, load optimized defaults, restart, and then make any changes you had in the BIOS.