Certain flash drives not opening on my computer

Certain pen drives do get detected on my PC, but they cant be opened. Refreshing the explorer solves the problem sometimes. The wierd thing though is that these pen drives do open on other computers. Is this a virus problem, or a hardware problem with my computer ?
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More about certain flash drives opening computer
  1. possibly a hardware problem as the usb controller might not be integrated into the chipset on your motherbd or an aftermarket one was added to provide additional ports.
    Check your motherbds website for an updated usb driver.
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