Running games off USB drive?

Hello I was wondering if I could run modernish games (planetside 2, league of legends) off a USB drive. Recently my hard drive broke but windows in on a small ssd. Could I run games off a usb and still have them playable?
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  1. depends on the speed of the usb drive but I wouldn't bother trying unless its a fast usb3 drive and you have a pc with usb3.
  2. Best answer
    usb has terrible IO and i am afraid you could break it in only 10x times usage because of intense IO
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