What's your budget for the motherboard? What do you plan for storage? # of drives, etc
ASUS P8Z68-M Pro
Asus Maximus IV Extreme GENE-Z
Asus Maximus IV Extreme-Z
Can Aftr Effects CS5 utilize the gpu muscle? If you don't plan to use SLI, you can find many non-SLI boards for under $150 and still have your choice of chipsets: z68, p67, etc.