I've tried several different configurations for the Harmony One including the one you suggested. The CD that came with the Hauppauge tuner didn't have anything except the drivers and what it calls the CIR config tool. That doesn't do anything except identify the IR receiver and associate it with WMC. What's puzzling is that I feel like that should work. Yet I've done it over and over using different setups for the remote and none of them respond. It's very frustrating.