as long as your mother board have PCI-E slot it will
But the GTX 260 is longer than the card that I am currently using and the SATA ports and cables are on the way... Is it possible to transfer the connection of the SATA cables on the lower part SATA ports? My hard drive and dvd drive are plugged on the upper two SATA ports, can I transfer those two cables on the lower two SATA ports? Are all those SATA ports are all the same?
lol. i know what you mean you should be more clear with your question. you mobo will be fine but your case might not. if the HDD is in the way you can move those HDD on the lower deck. if you can't that just plug those SATA cable on the lower side of your mobo. SATA ports are compatible with all device supporting SATA