Look at the brand of mouse you have and see if it has a model number. Search for the latest mouse driver via the internet and download. Restart computer and give it another go. I had an issue with this several years ago with an HP pavilion computer and one solution that works, albeit a temporary fix, is to unplug and replug the usb mouse connection when the problem occurs. This will usually fix the problem for a time. You can always get a new mouse - They aren't much money for the standard ones