It should work. You should begin by setting the RAM voltage to 1.65V in the BIOS, then save the settings and exit the BIOS screen. The system will re-start.
At that point I would boot to run memtest86+, testing one stick of RAM at a time. If all pass, then test them all together. If memtest86+ fails at the 1.65V setting, try increasing the RAM to 1.7V and run memtest86+ again.
After all 4 sticks of RAM pass memtest86+, boot to the OS and run whatever you do for system tests and benchmarking.