Thanks for the help and advice in advanced. I have replaced numerous components, yet have never built from the ground up. After reading numerous other build forums and Tom’s advice, this is the component list I have come up with. Any advice is most welcome!
The Core i7-2600K will run CS 5 better than the Core i5-2500K, although once overclocked you probably won't notice the difference. I would highly advise going with a Nvidia video card. CS 5 introduced a lot of hardware acceleration features that only run on Nvidia cards.
Check out this article for the details on CS 5 and hardware acceleration. I would specifically recommend a GTX 560-GTX 570. Both are about in the same range as the Radeon.
RAM has to perform operations in multiple steps, Column Access Strobe refers to the delay between a certain key step that has to be performed as part of memory accesses. If you want to pick up 16GB of RAM that probably wouldn't be a bad idea. RAM is so dirt cheap and it won't hurt anything to add extra, besides, photoshop loves RAM.
OK So here is some of my suggestions off foscooter's.
1) Don't get the Asus Pro board, not even worth it at its price when it has the same things that the Asrock Extreme4 offers. IMO Go with the Asrock Extreme4 P67. With the BIOS update that Asrock just came out with, the 2500K OCs to 5.1ghz on air cooling.
2) Don't get the 6850 in Crossfire, the room for expandability that your left with is kind of minimal because I doubt you will even go Tri-fire. So I suggest getting either 2 6950 1GB and run those in crossfire (they out perform a single 5970 and a single 580) or you could go with a single 6950 2GB which will run you 300$ but in the end you can unlock it to a 6970 2GB.
6950 CF performance: http://www.techpowerup.com/reviews/ASUS/Radeon_HD_6950_...
3) Instead of that PSU go for the XFX 850, it's cheaper and for practically the same performance (wattage/efficiency) HardOCP did a review on the XFX 850 and it was very close to 80+ Gold failing in only one test.
4) Crucial SSDs are hardly worth there price mainly because of their controllers. One thing is the fact that Crucial SATA III SSDs perform at Sandforce SATA II SSDs level. So for instance the Vertex 2 is pretty close to crucial SATA III ssds. If you want a good SATA 3 SSD for its price, wait for OCZ to release the Vertex 3 or wait for Sandforce to release the SF-2000 Controller. 480 mb/s reads boasts OCZ.
5) Get the Hyper 212+ off Amazon, cheaper, extra fan, and free shipping. You can find it off the site in my siggy or just go to amazon.
Thanks for the great suggestions. I think I will get 2 kits of the RAM and go ahead and bump it up to 16GB. I am still not sure on the Motherboard, deciding between the Asus P8P67 Pro and the Asrock Extreme4 P67. I have read reviews on each and both seem comparable. I will be getting the Hyper 212+ off Amazon. And it looks like I will switch over to an Nvidia card. I have always used Radeon, but the Nvidia cards have always been strong.
Because of CS 5 NVidia acceleration, I think it could be nice to go that way. For this reason alone I would consider the new GTX 560 Ti; not that it's not good, I just think it falls in some kind of no-market zone between the HD6870 and the HD6950.