I might be wrong, but, I don't think the 259.22 drivers are the latest atm. Make sure to check Nvidia.com for the latest reference drivers. You don't have to use the MSI ones and generally IMO, the reference drivers are better and more frequently updated.
Also, it seems possible you could have some residual video drivers or settings that are causing your issue. You could always try removing the drivers and restarting in safe mode. Also try running a driver cleaner utility while your in safe mode to eliminate that as a possible issue.