Hi there Jim,
It should, it doesn't state no ATAPI dev.
If u will run out of the ports, u can still use it with SSD/HDD and hook up DVD drive into the Red one : ) But, it will work,...
Thanks nikorr, I have the SATA 4 connection port available for my Asus SATA ODD. Since the MB manual isn't too specific about connecting SATA ODD's to a motherboard SATA port I was concerned about installing it at all. I will go ahead and try it tomorrow. Other blogs suggest that since the OS is already installed that there shouldn't be a problem, especially with Vista and Windows 7.