That's easy
... simply a specs thing. CAs 6 is better than CAs 7 which is better than CAS 8 and so on
2 x 2GB set = DDR3-1600 CAS 6
http://www.newegg.com/Product/Product.aspx?Item=N82E16820226182
2 x 4Gb set = DDR3-1600 CAS7
http://www.newegg.com/Product/Product.aspx?Item=N82E16820226179
PSU - How'd ya pick a 1200 watt PSU before picking ya vid cards ?
$500-ish cards
single card - GTX 580
possible SLI/CF in future - GTX 580
The 580 doesn't really have competition at the top spot
$350-ish cards
single card - GTX 570 or 6970
possible SLI/CF in future - GTX 570
The 570 and 6970 are as equal as any two cards I have seen from both camps, however when paired, SLI's scaling advantage makes this a narrow win for the 570
$250-ish cards
single card - GTX 560 Ti
possible SLI/CF in future - GTX 560 Ti
560's overclockabilityy is the key here:
http://www.overclockersclub.com/reviews/nvidia_asus_gtx560ti/17.htm
The performance was good right out of the box with both of these cards and when it came time to overclock them, I was able to hit over 1GHz on the GF114 cores of both cards and well over 1150MHz on the GDDR5 memory. These bumps in performance from overclocking were not just small bumps, but significant jumps in performance, allowing the GTX 560 Ti from NVIDIA and ASUS to wipe the floor with the HD 6870, its direct competitor.
For the 560's at stock, you'd want the XFX Black edition 750. It matches up well with the HX750 (same 10.0 performance rating @ jonntguru.com) but is way cheaper than the hx.
For the 560's overclocked or the 570's, you'd want the XFX Black edition 850 or the Antec CP-850. Both matches up well with the HX850 (same 10.0 performance rating @ jonntguru.comand CP stands alone for quietness ) but both way cheaper than the HX.
For the 580'S, you'll want 900 - 1000 watts. Lotta options here:
Antec CP-1000 ($150)
Antec HCP-1200 ($310)
Corsair HX1000 ($215)
Corsair AX1200 ($280)
Looking at your HAF-X / AX1200 combo at $460....ya gotta look at the DF-85 / CP-1000 combo at $310. The $150 difference will go a long way towards paying for other upgrades. I have built with both and prefer the DF-85. The larger CPX form factor CP series PSU's give Antec an almost unfair advantage as the extra size comes in handy when trying to keep a PSU quiet and cool running.