What are the advantages/disadvantages (if there are any) of having an Intel processor paired with an nvidia graphics card opposed to a radeon graphics cards? Same goes for AMD processors paired with either of the 2 brands of graphics cards.
Or does it not matter at all?
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Really doesn't matter.
Except ATI circuit boards are made from ground up puppy bones.
It makes no known difference unless you want to use Crossfire, SLI or PhysX.