Itunes in-game lag

When I have itunes playing while I'm in game, I feel like my game is sketchy. It's kind of hard to describe what exactly it's like. I am always getting above 125fps the entire time I play any game. It plays normally except every couple of seconds it freezes really fast. It makes it really hard to play and the only way to stop it is by closing itunes (which means I can't listen to music while I play). I have my mamba wired and keyboard isn't even wireless. I'm not sure what it's doing that screws everything up.
I know for sure that it's not a soundcard issue because I could always listen to music before while I played. I can also listen while I'm not in-game. The only thing I have that's different is a new keyboard. I have been through 6 keyboards in 2 weeks and only one of them did this.
They all broke (mostly my fault) and I tried new ones
-Microsoft Ergonomic keyboard 4000 (no issues)
-Logitech G15 (no issues)
-Razer Lycosa (no issues)
-Microsoft Wave (weird latency issues after 1st day, it was wireless though...)
-Steelseries Merc Stealth (no problems)
-Saitek Cyborg (current keyboard: having momentary in game freezing).
It did this yesterday and today. Also, today I am using a new mouse but I doubt this has anything to "contribute to it"

A friend of mine also bought the same keyboard the same day and he doesn't have any problems in any games.
I tried re-installing itunes and I uninstalled my keyboards drivers (I don't need them anyway). No luck.

It doesn't do it with pandora or windows media player either. The sound quality is fine when I use both of those and in-game is smooth. No issues.
I've never had this problem before and I don't know what would be causing it, any ideas?

pc specs listed at the bottom of the page in the link
http://www.xfire.com/profile/thesnakedoctor8