Thanks for the suggestions everyone. Overall, I got the game to work. I just uninstalled both PhysX and ME2, then reinstalled PhysX and THEN the game. It works just fine now and is a bloody awesome game. Problem I had last time was I didn't have PhysX installed but installed ME2, so when ME2 searched for PhysX it couldn't find it, so I downloaded PhysX, but it still couldn't find it, so with uninstalling both the game and driver, I effectively did like a refresh of the ME2's recognition of the PC's driver list; at least that's the best explanation I could come up with. Again, thanks to everyone who gave out some suggestions, it really helped and now I can enjoy my $20.00 I spent.